Dental Health Info

Older adults with more harmful than healthy bacteria in their gums are more likely to have evidence for amyloid beta -- a key biomarker for Alzheimer's disease -- in their cerebrospinal fluid, according to new research. However, this imbalance in oral bacteria was not associated with another Alzheimer's biomarker called tau.

Scientists report that an antibody for one gene -- uterine sensitization associated gene-1 or USAG-1 -- can stimulate tooth growth in mice suffering from tooth agenesis.

Research shows that periodontitis, severe gum disease, is linked to higher blood pressure in otherwise healthy individuals. This study of 500 adults with and without gum disease found that approximately 50% of adults could have undetected hypertension. Promotion of good oral health could help reduce gum disease and the risk of high blood pressure and its complications.

An ion channel called TRPC5 acts as a molecular cold sensor in teeth and could serve as a new drug target for treating toothaches.

Scientists has found evidence that SARS-CoV-2, the virus that causes COVID-19, infects cells in the mouth. The findings point to the possibility that the mouth plays a role in transmitting SARS-CoV-2 to the lungs or digestive system via saliva laden with virus from infected oral cells. A better understanding of the mouth's involvement could inform strategies to reduce viral transmission within and outside the body.

People's teeth-chattering experiences in the dentist's chair could be improved by fresh insights into how tiny, powerful bubbles are formed by ultra-fast vibrations, a study suggests.

People with periodontitis are at higher risk of experiencing major cardiovascular events, according to new research.

According to some estimates, chronic pain affects up to 40% of Americans, and treating it frustrates both clinicians and patients -- a frustration that's often compounded by a hesitation to prescribe opioids for pain.

Bleeding of the gums on gentle probing, or gingival bleeding tendency, and also bleeding in the eye, or retinal hemorrhaging, were associated with low vitamin C levels in the bloodstream.

Got milk? The 1990s ad campaign highlighted the importance of milk for health and wellbeing, but when did we start drinking the milk of other animals? And how did the practice spread? A new study led by scientists from Germany and Kenya highlights the critical role of Africa in the story of dairying, showing that communities there were drinking milk by at least 6,000 years ago.

The main nonpsychoactive component of cannabis has been shown to kill the bacteria responsible for gonorrhoea, meningitis and legionnaires disease, which could lead to the first new class of antibiotics for resistant bacteria in 60 years.

Research has been used to shape how dentistry can be carried out safely during the COVID-19 pandemic by mitigating the risks of dental aerosols.

The human body is filled with friendly bacteria. However, some of these microorganisms, such as Veillonella parvula, may be too nice. These peaceful bacteria engage in a one-sided relationship with pathogen Porphyromonas gingivalis, helping the germ multiply and cause gum disease, according to a new study.

An imbalance of the body's oxygen producing free radicals and its antioxidant cells could be the reason why gum disease and chronic kidney disease affect each other, a new study has found.

Researchers have examined the human oral microbiome and discovered tremendous variability in bacterial subpopulations living in certain areas of the mouth. In many cases, the team was able to identify a handful of genes that might explain a particular bacterial group's habitat specificity.

Researchers have found that careful selection and operation of dental drills can minimize the spread of COVID-19 through aerosols.

Researchers have identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body.

Researchers report a cross-linker for dental cement that breaks down under UV light, making treatments easier to reverse.

A new article describes for the first time how minerals come together at the molecular level to form bones and other hard tissues, like teeth and enamel.

The stress and anxiety experienced by the general population during Israel's first lockdown brought about a significant rise in orofacial and jaw pain, as well as jaw-clenching in the daytime and teeth-grinding at night, according to a new study.

Roughly half of US dentists experienced verbal or reputational aggression by patients in the past year, and nearly one in four endured physical aggression, according to a new study.

Scientists have described the earliest known example of dentary bone with two rows of cusps on molars and double-rooted teeth. The new findings offer insight into mammal tooth evolution, particularly the development of double-rooted teeth.

Studying bacterial biofilms, scientists have discovered that mechanical forces within them are sufficient to deform the soft material they grow on, e.g. biological tissues, suggesting a 'mechanical' mode of bacterial infection.

Researchers showed that laser ablation of bone inhibits expression of the osteogenesis inhibitor protein sclerostin without causing inflammation, unlike the conventional bur-drilling technique. Further investigations confirmed that this beneficial bio-stimulation works by inducing mechanical stress. These findings help advance research into the treatment of osteoporosis as well as specific enhancement of bone regrowth in orthopedic and dental surgery.

Scientists have discovered that a specific type of molecule may stimulate stem cells to regenerate, reversing the inflammation caused by periodontal disease.

New knowledge on the cellular makeup and growth of teeth can expedite developments in regenerative dentistry - a biological therapy for damaged teeth - as well as the treatment of tooth sensitivity.

Researchers have examined the sustainability of different models of the most commonly used oral health product - the toothbrush - to ascertain which is best for the planet and associated human health.

If the mist in a dentist's office -- sent flying into the air by spinning, vibrating tools -- contains a virus or some other pathogen, it is a health hazard. So researchers studied the viscoelastic properties of food-grade polymers and discovered that the forces of a vibrating tool or dentist's drill are no match for them. Not only did a small admixture of polymers completely eliminate aerosolization, but it did so with ease.

Eating sugar or other carbohydrates after dental cleanings causes oral bacteria to quickly rebuild plaque and to produce acids that corrode tooth enamel, leading to cavities. Today, scientists report a treatment that could someday stop plaque and cavities from forming in the first place, using a new type of cerium nanoparticle formulation.

Reports show that cancer is the second leading cause of death globally. Scientists have found DNA mutations in some cancers that link them to a bacterial toxin called colibactin. Their findings improve understanding of how some cancers develop, and could help in their prevention.

Researchers used atomic force microscopy to quantitatively evaluate how acidic and sugary drinks affect human tooth enamel at the nanoscale level. This novel approach is useful for measuring mechanical and morphological changes that occur over time during enamel erosion induced by beverages.

Researchers combined complementary imaging techniques to explore the atomic structure of human enamel, exposing tiny chemical flaws in the fundamental building blocks of our teeth. The findings could help scientists prevent or possibly reverse tooth decay.

People who have periodontal (gum) disease may have a higher risk of developing some forms of cancer.

Medicated chewing gum has been recognized as a new advanced drug delivery method but currently there is no gold standard for testing drug release from chewing gum in vitro. New research has shown a chewing robot with built-in humanoid jaws could provide opportunities for pharmaceutical companies to develop medicated chewing gum.

Researchers have cracked one of the secrets of tooth decay. The materials scientists are the first to identify a small number of impurity atoms in human enamel that may contribute to the material's strength but also make it more soluble. They also are the first to determine the spatial distribution of the impurities with atomic-scale resolution. The discovery could lead to a better understanding of human tooth decay as well as genetic conditions that affect enamel formation.

Microorganisms on the tongue could help diagnose heart failure, according to new research. 'The tongues of patients with chronic heart failure look totally different to those of healthy people,' said one of the researchers.

A new collaborative study reveals that inflammatory bowel disease (IBD) may be the latest condition made worse by poor oral health via a clash between the mouth and gut microbiomes.

A research team evaluated 14 different types of Sichuan pickles from southwest China. They extracted 54 different strains of Lactobacilli and found that one, L. plantarum K41, significantly reduced the incidence and severity of cavities. K41 was also highly tolerant of acids and salts, an additional benefit as a probiotic for harsh oral conditions. It also could have potential commercial value when added to dairy products.

It's not just the presence of bacteria that can lead to disease; their spatial arrangement also matters. When scientists examined the bacteria that causes tooth decay, they found it 'shields' itself under blankets of sugars and other bacteria in a crown-like arrangement, helping it evade antimicrobials and concentrate its tooth-damaging acids.

The results of a new study demonstrated that community water fluoridation is not associated with increased risk of osteosarcoma.

A drug that has life-extending effects on mice also reverses age-related dental problems in the animals, according to a new study.

Researchers have developed a new automatized way to localize mandibular canals.

For the first time, researchers have shown that a unicellular parasite commonly found in the mouth plays a role in both severe tissue inflammation and tissue destruction.

Teeth constitute a permanent and faithful biological archive of the entirety of the individual's life, from tooth formation to death, a team of researchers has found. Its work provides new evidence of the impact that events, such as reproduction and imprisonment, have on an organism.

The first study looking at the effect of chlorhexidine mouthwash on the entire oral microbiome has found its use significantly increases the abundance of lactate-producing bacteria that lower saliva pH, and may increase the risk of tooth damage. "In the face of the recent COVID-19 outbreak many dentists are now using chlorhexidine as a pre-rinse before doing dental procedures. We urgently need more information on how it works on viruses," said one of the researchers.

Researchers show that different stem cell populations are innervated in distinct ways. Innervation may therefore be crucial for proper tissue regeneration. They also demonstrate that cancer stem cells likewise establish contacts with nerves. Targeting tumor innervation could thus lead to new cancer therapies.

The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say researchers.

A protein that normally deposits mineralized calcium in tooth enamel may also be responsible for calcium deposits in the back of the eye in people with dry age-related macular degeneration (AMD), according to a new study.

Researchers found that post-stroke patients re-grow a healthy microbiota in their mouth and gut when they revert to normal food intake from tube feeding. These results emphasize the need to actively normalize feeding in these patients, not only to minimize the risks of tube feeding, but also because oral feeding significantly alters the microbiome of both the mouth and the gut, potentially with beneficial consequences for overall health.

Most people know that good oral hygiene -- brushing, flossing, and regular dental visits -- is linked to good health. Microbiome researchers offer fresh evidence to support that conventional wisdom, by taking a close look at invisible communities of microbes that live in every mouth. Their study found a correlation between people who did not visit the dentist regularly and increased presence of a pathogen that causes periodontal disease.

For decades, researchers have suggested a link between oral health and inflammatory diseases affecting the entire body -- in particular, heart attacks and strokes. Results of a randomized pilot trial of Plaque HD®, the first toothpaste that identifies plaque so that it can be removed with directed brushing, showed that it produced a statistically significant reduction in C-reactive protein, a sensitive marker for future risks of heart attacks and strokes, among those with elevations at baseline.

Exposing teeth to excessive fluoride alters calcium signaling, mitochondrial function, and gene expression in the cells forming tooth enamel -- a novel explanation for how dental fluorosis, a condition caused by overexposure to fluoride during childhood, arises.

Children with higher concentrations of a certain chemical in their blood are more likely to get cavities, according to a new study. Researchers found that higher concentrations of PFAS were associated with greater tooth decay in children.

One of the causes of breast cancer may be inflammation triggered by harmful bacteria suggest researchers. Scientists advise consuming natural yogurt, which contains beneficial bacteria which dampens inflammation and which is similar to the bacteria found in breastfeeding mothers. Their suggestion is that this bacteria is protective because breast feeding reduces the risk of breast cancer. The consumption of yogurt is also associated with a reduction in the risk of breast cancer.

Cavities, or dental caries, are the most widespread non-communicable disease globally, according to the World Health Organization. Having a cavity drilled and filled at the dentist's office can be painful, but untreated caries could lead to worse pain, tooth loss, infection, and even illness or death. Now, researchers report a bioactive peptide that coats tooth surfaces, helping prevent new cavities and heal existing ones in lab experiments.

Researchers have succeeded in extracting a complete human genome from a thousands-of-years old 'chewing gum.' According to the researchers, it is a new untapped source of ancient DNA.

Obesity and gum (periodontal) disease are among the most common non-communicable diseases in the United States -- and studies show these chronic conditions may be related. This new study explores the effect of obesity on non-surgical periodontal care and evaluates potential pathways that may illustrate the connection between the two conditions.

Brushing teeth frequently is linked with lower risks of atrial fibrillation and heart failure, according to a new study.

Three-year trial comparing three treatment strategies for tooth decay in children's teeth finds no evidence to suggest that conventional fillings are more successful than sealing decay into teeth, or using preventive methods alone. 43% of those participating in the study experienced toothache or dental infection regardless of the treatment received.

Researchers have found that a person's first permanent molars carry a life-long record of health information dating back to the womb, storing vital information that can connect maternal health to a child's health, even hundreds of years later.